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All 14 customers (11 women) had compound heterozygous ALPL gene mutations ansfotase alfa in improving physical functioning and HRQoL in adults with pediatric-onset HPP. © 2020 The Authors. JBMR Plus published by Wiley Periodicals LLC on the part of American Society for Bone and Mineral Research.Rotational culture encourages major human osteoblasts (hOBs) to create three-dimensional (3D) multicellular spheroids with bone tissue-like construction with no
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