https://www.selleckchem.com/pr....oducts/gsk2643943a.h
Over the 6-year follow-up, 3596 individuals developed colorectal cancer. Estimated intention-to-treat and per-protocol hazard ratios were 1.00 (95% confidence interval [CI] 0.87, 1.16) and 0.90 (95% CI 0.71, 1.12), respectively. As expected, adequate case-control sampling yielded the same estimates. By contrast, previous case-control analytical approaches yielded estimates that appeared strongly protective (odds ratio 0.57, 95% CI 0.36, 0.91, for ≥5 vs. 5 years of statin use). Our study demonstrates how to explicitly emulate a t
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