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ADHD Medications - What Are the Side Effects? Many people with ADHD take medication for the condition. It can improve symptoms but it can also trigger negative side effects. If you experience any adverse effects, speak to your GP about them. The most common prescription medication prescribed by healthcare professionals for ADHD is stimulants. These medications increase the levels of brain chemicals known as neurotransmitters, that regulate the attention span and behavior. Methylphenidate