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https://www.selleckchem.com/pr....oducts/rituximab.htm
The APOE-ε4 gene showed little impact on symptom development when included as a predictor. CONCLUSIONS Our findings provide support for the concept that younger-onset AD is associated with the progressive development of more non-memory symptoms beyond the first time point. Associations between symptoms were evident, which may reflect that pathology can remain isolated in a network for some time. APOE-ε4 status had little influence on cognitive symptom development which may indicate that the effect it has occurs very early in the disea