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com/mutalyzer/mutalyzer) and a running instance is available at https//mutalyzer.nl. Mutalyzer is an Open Source project under the GNU Affero General Public License. The source code is available on GitHub (https//github.com/mutalyzer/mutalyzer) and a running instance is available at https//mutalyzer.nl.The management of patients with glioma usually requires multimodality treatment including surgery, radiotherapy, and systemic therapy. Accurate neuroimaging plays a central role for radiotherapy planning and follow-up after radiotherapy