https://www.selleckchem.com/pr....oducts/Rapamycin.htm
001), and then increased in the stage 2 (P = 0.008). SNAP individuals also had significantly increased CSF sTREM2 (P less then 0.001). Results of multiple linear regressions also showed positive correlations of CSF sTREM2 with Aβ1-42 (β = 0.192, P less then 0.001), T-tau (β = 0.215, P less then 0.001) and P-tau (β = 0.123, P less then 0.001). CONCLUSION CSF sTREM2 levels are dynamic in preclinical AD. Aβ pathology is associated with a decrease in CSF sTREM2 in the absence of tau deposition and neurodegeneration. However, tau path
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