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Finding the Best ADHD Medication For Adults The use of medications is the foundation of many adult ADHD treatment strategies for adults with ADHD. Finding the right medication dosage and dose isn't always straightforward. Stimulants: These drugs can be used to treat both hyperactivity as well as inattention. They work by increasing levels of chemicals in the brain that transmit messages between nerve cells. They are administered several times per day and begin working in less than one hour. Stimulants Stimulants are among the first drugs