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Anterior bone loss (ABL) is a relatively easily neglected condition after cervical disc replacement (CDR). Whether this phenomenon is a radiological anomaly or a complication remains controversial. Several studies have reported the clinical characteristics of ABL and speculated on the pathogenic mechanism based on a certain type of artificial disc, while the overall understanding of ABL is lacking. To describe the prevalence, impacts, and risk factors of ABL after CDR. We searched the PubMed, Cochrane Library, and Excerpta Medica databa