https://www.selleckchem.com/
Lithium carbonate (Li CO ) is widely used in the treatment of clinical-affective psychosis. Exposure to Li CO during pregnancy increases the risk of neural tube defects (NTDs) in offspring, which are severe birth defects of the central nervous system. The mechanism of Li CO -induced NTDs remains unclear. C57BL/6 mice were injected with different doses of Li CO intraperitoneally on gestational day 7.5 (GD7.5), and embryos collected at GD11.5 and GD13.5. The mechanisms of Li CO exposure-induced NTDs were determined utilizing immunohistochemistry, western blot
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