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How to Choose the Best ADHD Medication for Adults With Anxiety and Depression When a person suffers from both ADHD and anxiety or depression, addressing the first disorder can improve the second. Mental health professionals typically prescribe antidepressants or stimulants for depression along with an ADHD medication. Wellbutrin (bupropion), and Effexor, (venlafaxine), are the two most common antidepressants prescribed to treat ADHD "off-label". These drugs increase the levels of
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