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The KD estimator provides reliable coverage of τ2 . Inverse-variance-weighted estimators of the overall effect are substantially biased, as are the Mantel-Haenszel odds-ratio and the estimators from the generalized linear mixed models. The SSW estimator of the overall effect and a related confidence interval provide reliable point and interval estimation of the overall log-odds-ratio. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.The quality of stem