https://www.selleckchem.com/pr....oducts/BafilomycinA1
Mesenchymal stem cells or their conditioned medium improve chronic wound healing, and their effect is enhanced by hypoxia. Diabetic foot ulcers are chronic wounds characterized by abnormal and delayed healing, which frequently require amputation. The authors evaluated the effect of topical application of conditioned medium from hypoxically cultured amnion-derived mesenchymal stem cells on wound healing in diabetic mice. Amnion-derived mesenchymal stem cells were cultured under 21% oxygen to prepare normoxic conditioned medium and
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