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How Does Medication For ADHD Work? Stimulants can increase your ability to focus and control impulses by increasing levels of dopamine and norepinephrine within your brain. They are available in immediate-release (short acting) and extended release tablets that can be taken once daily in the morning. have a longer time to work, but can also improve attention and impulse control. Atomoxetine (Strattera) and guanfacine (Viloxazine) are in the class of antidepressants and incr