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https://www.selleckchem.com/pr....oducts/bay-2402234.h
Ion channels self-organize on cellular and organelle membranes as clusters and mutually modulate their gating behavior. It has been reported that the efficient information transfer is achieved by cooperative clustering of ion channels. To address the origin and nature of collective dynamics in ion channel clusters, a statistical mechanical model, namely, the Zimm-Bragg-type model in two dimensions with unequal weight distribution in channel-channel interactions, has been proposed. Nearest neighbor interaction along with next-nearest