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The group with CCI ≥ 2 and RDI less then 70% had a poorer OS and EFS, as compared to the other three groups. The group with CCI less then 2 and RDI ≥ 70% had a superior OS but an identical EFS, as compared to the two groups with CCI less then 2 and RDI less then 70% and CCI ≥ 2 and RDI ≥ 70%. Conclusions CCI ≥ 2 was associated with a poorer outcome, but maintaining RDI ≥ 70% may improve the outcome, especially in elderly DLBCL patients.Introduction Biliary tract cancers (BTC) are rare malignancies arising from biliary system. Systemic