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How to Choose the Best ADHD Medication for Adults With Anxiety and Depression If someone has ADHD and anxiety or depression, treating one condition often improves the other. Mental health professionals usually prescribe antidepressants or a stimulant for depression, along with an ADHD medication. Wellbutrin (bupropion) and Effexor (venlafaxine) are the most frequently used antidepressants that are prescribed "off-label" for ADHD. These medications increase the levels of neurotransmitters dopamine and
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