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How to Choose the Best ADHD Medication for Adults With Anxiety and Depression If a person suffers from both ADHD and anxiety or depression, treating one condition often improves the other. Mental health experts prescribe antidepressants and stimulants for depression, or antidepressants along with ADHD medication. Wellbutrin (bupropion) and Effexor (venlafaxine) are the most frequently used antidepressants that are prescribed "off-label" for ADHD. These drugs increase levels of the neurotransmitters norepinephrine as w
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