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A region-of-interest (ROI) approach was then used to compare CBF to clinical and neuropsychological measures within the TBI group in a cross-sectional fashion, as well as to the degree of subsequent cognitive recovery among subjects with follow-up testing. At 3 months post-injury, the TBI group demonstrated lower performance in each cognitive domain (p less then 0.05), as well as widespread reductions in grey matter CBF independent of structural atrophy (p less then 0.05). Within the TBI group, CBF was moderately correlated with injury sev