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The non-group O patients received a median (IQR) volume of 1470 mL (1368-2052) of ABO-incompatible plasma. Comparing the non-group O to the group O recipients, there were no significant differences in the haptoglobin, LDH, total bilirubin, potassium, or creatinine concentrations at any of the time points. There were no reported transfusion reactions. Conclusion Receiving at least four LTOWB units was not associated with biochemical or clinical evidence of hemolysis.Objective Brain tissue oxygen (partial oxygen pressure [pO2 ]) levels are