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Moreover, two novel constraints, sample affinity consistency and sample affinity regularization, are devised to refine the features and achieve the mutual promotion of these two branches. Extensive experiments of synthetic and real LR cases are conducted on wireless capsule endoscopy and histopathology images, verifying that our proposed method is significantly effective for medical image diagnosis.In this paper, we present novel strategies for optimizing the performance of many binary image processing algorithms. These strategies are c