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No significant difference was seen between patient groups regarding bleeding after extractions ( =0.917). Warfarin use does not increase the risk of post-extraction bleeding and can therefore be continued during tooth extraction. Warfarin use does not increase the risk of post-extraction bleeding and can therefore be continued during tooth extraction. Papillon-Lefèvre syndrome (PLS) is a rare autosomal recessive disorder. These patients lose their teeth at a young age and are in need of prosthetic rehabilitation. The aim of this systematic