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01), as well as county-level walkability (p=0.03), and urban-rural designation (p=0.02). OWO remains a vital issue for U.S. youth, with substantial area-level variability. The additional uncertainty for underrepresented groups shows surveys need to better target diverse samples.Irritable bowel syndrome (IBS) has been associated with copper-zinc imbalance and a zinc deficient diet. This study used Mendelian randomization to evaluate if genetically determined copper and zinc levels play a causal role in the development of IBS. Three single