https://www.selleckchem.com/pr....oducts/avitinib-ac00
miR-147b was found in much larger amounts in MSC-IL-Exo than in MSC-Exo. The miR-147b mimic significantly inhibited the expression of inflammatory cytokines, while the miR-147b inhibitor only partially blocked the anti-inflammatory effect of MSC-IL-Exo. MSC-IL-Exo and miR-147b mimic inhibited the reduction of IκBα, an nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κ inhibitor, by IL-1β and TNF-α. This study showed that MSC exosomes with IL-1β priming exhibit significantly enhanced anti-inflammatory activity
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