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Our results suggest that, within a social group, individuals may weight others' opinions through indirect reciprocity, highlighting the emergence of normative distortions in the process of information transmission among humans.The myeloid inhibitory receptor CLEC12A negatively regulates inflammation. Reduced CLEC12A expression enhances inflammation in CLEC12A knock-out mice with collagen antibody-induced arthritis. Moreover, CLEC12A internalisation augments human neutrophil activation. We thus postulated that CLEC12A expression on circ