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ADHD Medications For Adults Stimulants can help regulate the levels of chemical messengers that control the brain's attention. They are the first line of treatment to treat ADHD. They aren't thought to be habit-forming, however they can trigger adverse effects, like headaches and sleep problems. Your doctor might also prescribe guanfacine (brand names Tenex and Intuniv) or clonidine (Catapres) to decrease hyperactivity and impulsivity. These medications are more effective than stimulants. S