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Medication For ADHD - What Are the Side Effects? Many people suffering from ADHD have their symptoms improved through medication. But every person reacts differently to different drugs, and adverse reactions can be problematic. Methylphenidate is a stimulant. It is a stimulant that increases levels of a substance in the brain that helps control the attention span and behavior. Stimulant medication Stimulants enhance concentration and attention in 70% to 80percent of children and adults who take them. They affect the a