https://www.selleckchem.com/pr....oducts/incb084550.ht
To assess the dosimetric feasibility of a stereotactic body radiotherapy (SBRT) dose escalated protocol, with a simultaneous integrated boost (SI and a simultaneous integrated protection (SIP) approach, in patients with locally advanced pancreatic cancer (LAPC). Twenty LAPC lesions, previously treated with SBRT at our Institution, were re-planned. The original prescribed and administered dose was 50/30/25 Gy in five fractions to PTV (tumor-vessel interface [TVI])/PTV (tumor volume)/PTV (overlap area between PTV and planning organs