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sk individuals. Automated Drug Supplying and management System (ADS) are effective devices that secure drug's circuit and reduce hospital's expenses. The purposes of this study are to estimate the earnings made from ADS through a cost-benefit medical economic study, to highlight its impact on Central Chemotherapy Preparation Unit's (CCPU) global organization, its ergonomy and staff's satisfaction. Measurement of cytotoxic drug's consumption, expiration losses, pharmacy staff's working time, drugs stock-out before and after the implement