https://www.selleckchem.com/pr....oducts/linderalacton
After binding to the Oct4 promoter, Oplr16 recruited TET2 to induce DNA demethylation and activate Oct4 in fibroblasts, leading to enhanced reprogramming. These data suggest that Oplr16 may act as a pivotal chromatin factor to control stem cell fate by modulating chromatin architecture and DNA demethylation. © The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.Transmission of direct-acting antiviral(DAA) resistance associated substitutions(RAS) could hamper hepatitis C virus (HCV) cure ra
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