https://www.selleckchem.com/pr....oducts/paeoniflorin.
We performed this meta-analysis in order to assess the effect of melatonin on postoperative pain and perioperative opioid consumption. We systematically searched PubMed, EMBASE, and the Cochrane Library until October 2019 for studies concerning the effect of melatonin vs. placebo on postoperative pain. We also searched for grey literature in ClnicalTrials.gov and grey literature databases, including OpenGrey and Grey Literature Report. We performed a meta-analysis of postoperative pain scores, perioperative opioid use, the number o
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