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18). Genes in the modules were enriched with biological processes that have separately been found to be involved in either bone metabolism or atherosclerosis. The gene modules and their most significant member genes identified in this study support the osteoporosis-atherosclerosis comorbidity hypothesis and can provide new joint biomarkers for both diseases and their dual prevention.The iron mine tailings accumulation in dams is an environmental and economic problem. The composite based on high-density polyethylene/iron mine tailing pro