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7 predominantly in heterosexuals in these countries.Bile acids have contributed immensely to hydrogel research due to their peculiar physicochemical properties and biocompatibility. The wide accessibility of bile acids and their straightforward derivatization methods make them attractive building blocks for the design of novel hydrogels systems to deliver biomolecules, drugs, and vaccines. This review conceptualizes recent developments in bile acid-based hydrogels and their applications. These bile-based hydrogels have the ability to a