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In multivariate analysis, age was an independent risk factor of MCI aggravating, while attention (MoCA) was independent protective factor for MCI progression.Conclusions Age and worsening attention but not depression in MCI patients were independently associated with the progression of dementia in a 6-year follow-up period.As a by-product during flour production, wheat bran is mainly used as raw material for fodder or fermentation. In the present work, wheat bran was extruded with different moisture conditions and the consequently chemi
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