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ADHD Medications For Adults Stimulants aid in adjusting the levels of chemical messengers in the brain that control attention. They are the first line of treatment to treat ADHD. They aren't believed to be habit-forming, but they can have negative side effects, including headaches and difficulty sleeping. Your doctor could also prescribe Guanfacine (brand names Tenex and Intuniv) or clonidine (Catapres) to reduce hyperactivity and impulsivity. These medications are more effective than stimulants. Stimulants The most commonly prescribed medicat