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https://www.selleckchem.com/pr....oducts/guanosine-5-t
Objective  This study was aimed to compare the closure of skull base defect in endoscopic endonasal transsphenoid surgery of pituitary tumors, using bipedicled nasal septal flap versus fascial closure. The study hypothesis being that bipedicled nasal septal flap is better, compared with fascial closure of skull base defect post-endoscopic endonasal transsphenoid surgery of pituitary tumors. Methods  All the eligible patients were randomly divided into two groups and then randomly allocated to the surgeons