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The amount of itraconazole in nail clippings was quantified hereafter using a validated HPLC method. RESULTS Statistical analysis showed that itraconazole transungual permeation was not influenced by the studied monoterpenes (P value .05). CONCLUSION These results provided a new perspective for designing topical dosage forms for the treatment of onychomycosis. © 2020 Wiley Periodicals, Inc.BACKGROUND/OBJECTIVES Despite the apparent efficacy and favorable toxicity profile of TKIs, allogeneic SCT remains the only curative treatment fo