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In the current up to date, the gold standard to define the tissue technical behavior is represented by experimental tests, calling for the harvesting of ex-vivo specimens. In the past few years though, image-based approaches for the in vivo estimation of arterial muscle tightness were provided. The goal of this research is to determine an innovative new approach to deliver neighborhood distribution of arterial tightness, expected since the linearized Young's Modulus, on the ba