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Four identified hits presented an improved binding profile as compared to their parent analog anthrafuran 1. One derivative, anthrathiophene 2 demonstrated excellent in vitro inhibition of AurB (7.3 μM).In this paper, we aim to analyze the structure of formal logic in relation to its emergence as a universal tool for understanding and description of reality. There are some extended variations of logic that treat time and/or space (e.g. temporal logic), however in general, formal logic is regarded as universal. This universality makes for
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