https://www.selleckchem.com/pr....oducts/ly2157299.htm
Use of the rat SCI models showed that miR-135a-5p could increase the Basso, Beattie, and Bresnahan (BB scores, indicating neurological function recovery. In conclusion, the miR-135a-5p-SP1-Bax/Bcl-2/caspase-3 and miR-135a-5p-ROCK-AKT/GSK3β axes are involved in functional recovery of SCI by regulating neural apoptosis and axon regeneration, respectively, and thus can be promising effective therapeutic strategies in SCI.MicroRNA 22 (miR-22) was found in diverse cardiovascular diseases to have a role in regulating multiple cellular pro
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