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Methyl-CpG-binding domain (MBD) proteins play important roles in epigenetic gene regulation, and have diverse molecular, cellular, and biological functions in plants. MBD proteins have been functionally characterized in various plant species, including Arabidopsis, wheat, maize, and tomato. In rice, 17 sequenceswerebioinformatically predicted as putative MBD proteins. However, very little is known regarding the function of MBD proteins in rice. We explored the expression patterns of the riceOsMBD family genes and identified 13 OsMBDs wi