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RR1-10.2196/22511. DERR1-10.2196/22511. To optimize their use of a new Health Information System (HIS), supporting health care providers require effective HIS education. Failure to provide this education can significantly hinder an organization's HIS implementation and sustainability efforts. The aim of this review is to understand the most effective educational strategies and approaches to enable health care providers to optimally use an HIS. Ovid MEDLINE, Ovid Embase, EBSCO Cumulative Index to Nursing and Allied Health Literature,