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Increased transfusion rates correlated with lengthier ICU admission (p≤0.01 regardless of blood product). Ongoing hemorrhage in women with severe PPH manifests subtly and often requires active intervention. Hemorrhage control is required to achieve physiological stabilization and minimize organ damage. Ongoing hemorrhage in women with severe PPH manifests subtly and often requires active intervention. Hemorrhage control is required to achieve physiological stabilization and minimize organ damage. 3-indoxyl sulfate (3-IS) is an indole met