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Moreover, there were 301 deaths after a mean follow-up of 7.42 ± 1.66 years. An odds ratio (OR) of 2.82 ([95% confidence interval (CI) 1.86; 4.35], p  less then  0.0001) for incident atrial fibrillation and an OR of 1.49 ([95% CI 1.13; 1.96], p = 0.0046) for incident cardiovascular disease per 1-standard deviation (SD) increase in MR-proANP levels were found. A 36% (hazard ratio 1.36 [95% CI 1.19; 1.55], p  less then  0.0001) higher risk of death was found per 1-SD increase in MR-proANP levels. CONCLUSIONS Noise annoyance may contribute