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A total of 21486 articles were retrieved. After 2 rounds of review, 1 cohort study and 7 case-control studies with 3326171 participants were included into the meta-analysis. The pooled analysis found that patients with AR had a significantly higher risk of SLE than individuals without AR with the pooled OR of 1.36 (95% CI 1.08-1.72; I of 80%). A significantly increased 1.4 fold risk of SLE among patients with AR was observed in this systematic review and meta-analysis. A significantly increased 1.4 fold risk of SLE among patients with AR
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