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Ecosystem water use efficiency (WUE) is a key indicator that depicts the carbon-water coupling relationship in terrestrial ecosystems. Separating the effects of climate change and human activities to the variation in WUE are essential for water resources and ecosystem management, especially for fragile ecosystems such as the Tibetan Plateau (TP). In this study, we introduced an analytical framework that combined the attribution approach with the elastic coefficient separation method to assess the impact of climate change and human activ