https://www.selleckchem.com/pr....oducts/rocaglamide.h
BACKGROUND Ferroptosis is a novel mode of non-apoptotic cell death induced by build-up of toxic lipid peroxides (lipid-ROS) in an iron dependent manner. Cancer-associated fibroblasts (CAFs) support tumor progression and drug resistance by secreting various bioactive substances, including exosomes. Yet, the role of CAFs in regulating lipid metabolism as well as ferroptosis of cancer cells is still unexplored and remains enigmatic. METHODS Ferroptosis-related genes in gastric cancer (GC) were screened by using mass spectrum; exosomes
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