https://ak7chemical.com/effect....-of-ecological-toxic
We show that coxsackievirus and adenovirus receptor (CXADR) is the cell-surface receptor for SFRP2 in retinoblastoma cells; that CXADR functions as a "dependence receptor," transmitting a growth-inhibitory sign within the lack of SFRP2; and that the balance between SFRP2 and CXADR determines nitric oxide manufacturing. Consequently, high SFRP2 RNA expression correlates with risky histopathologic features in retinoblastoma. Targeting SFRP2 signaling by SFRP2-binding peptides or by a pharmacological inhibito
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