https://www.selleckchem.com/pr....oducts/Staurosporine
It was suggested that group V secretory phospholipase A (sPLA2-V) existed in the nucleus. This study examined whether nuclear sPLA -V plays a role in endocytosis of acetylated low-density lipoprotein (AcLDL) in monocyte/macrophage-like cell line RAW264.7 cells. RAW264.7 cells were transfected with shRNA vector targeting sPLA -V (sPLA -V-knockdown [KD] cells) or empty vector (sPLA -V-wild-type [WT] cells). AcLDL endocytosis was assessed by incubation with I-AcLDL or AcLDL conjugated with pHrodo. Actin polymerization was assessed by
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