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https://www.selleckchem.com/pr....oducts/ly3039478.htm
In conclusion, the present design represents an important advance in bringing engineered cardiac microtissues closer to the native heart, overcoming traditional bulky off-chip fluid handling systems, improving microtissue performance, and matching oxygen and energy substrate requirements of metabolically active constructs, avoiding cellular hypoxia. Distinct flow patterns differently impact on microtissue performance and gene expression program. We sought to evaluate whether the cutaneous silent period (CSP) could be an electrophysiol