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These finer systems may help within the growth of a novel therapy to better suppress the ccRCC progression under different oxygenization conditions.Nobiletin, a polymethoxy flavone (PMF), is specific to citrus and it has been reported showing important health-supporting properties. Nobiletin has actually six methoxy groups during the 3',4',5,6,7,8-positions, which are catalyzed by O-methyltransferases (OMTs). Up to now, researches on OMTs in citric acid fruit are nevertheless restricted. I
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